Dr. Gooneratne’s research interests are centered around studying the nature of sleep disorders in the elderly. While many older adults complain of difficulties with sleep, it is an area about which modern medicine has only a limited understanding. Funded initially by a National Institute on Aging Mentored Research Career Development Award (K23), he is pursuing research examining the role of melatonin, a hormone secreted by the pineal gland, in sleep in the elderly and the effects of sleep apnea treatment on cognitive function in older adults. Dr.Gooneratne also runs a Sleep Disorders Clinic for Seniors in an effort to address the medical needs of older patients with sleep disorders. In addition, Dr. Gooneratne is the Associate Director of the Masters in Translational Research Program, with a focus on Entrepreneurial Science education at the University of Pennsylvania's ITMATEd program. He is the director of the mHealth mobile app development service at ITMAT (CTSA/Penn). He also helps to coordinate the research activities of the Geriatric fellows in the Division of Geriatric Medicine and mentors research fellows in the Division of Sleep Medicine.